Metformin Dosage means the amount of Metformin consumed at any one time. The dosage for Adults Diabetes Mellitus Type II is 500 mg twice a day. It is to be taken orally along with the morning and evening meal. Extended release is 500 to 2000 mg orally once daily. This is to be consumed together with the evening meal. Maximum daily dose is 2500 mg.
As regards Renal Dose Adjustments, Metformin should be used with caution. Patients with renal disease should take extra care. This is mainly due to the fact that its dosage can precipitate lactic acidosis. Similarly elderly patients should also take Metformin with caution as such patients are vulnerable to conditions like decreased renal function. As regards Liver Dose Adjustments, patients with liver disease should take the supplement with extra caution and must use the same only if necessary. It may precipitate lactic acidosis in liver patients.
Dose Adjustments: Its dosage can be increased by 500 mg every week or 850 mg every other week. However this should be done considering the tolerance level of the patient and the response level of the patient to the supplement . In the case of Metformin, a maximum daily dose of 2.55 grams is the most recommended quantity. It is permissible to use it along with oral sulfonylurea. While transferring patients from other oral hypoglycemic agents, extra care should be taken in order to prevent hypoglycemia.
Another use with caution: A few people will use it with alcohol and it may have some effects on them, for more information you can see this article – Metformin and Alcohol, the article give us a lot information about taking metformin together with alcohol and you can find out what you should do.
It is to be used as per the prescription provided by the doctor and no variation in the quantity is permitted. The doctor may or may not change the dosage to ensure the maximum positive results. It is usually to be used along with a meal, in some cases it is to be consumed once daily with the evening meal, however closely follow the doctor’s prescription.
Though every attempt has been made to mention the maximum possible dosage applicable to patients in varying conditions of illness, this should only be treated as a guideline. It is always better to consult your doctor for further assistance and clarifications related to the usage.